Anal Cancer

Anal Cancer

Treatment Options by Stage

In This Section
  • Stage 0 (Carcinoma in Situ)
  • Stage I Anal Cancer
  • Stage II Anal Cancer
  • Stage IIIA Anal Cancer
  • Stage IIIB Anal Cancer
  • Stage IV Anal Cancer

For information about the treatments listed below, see the Treatment Option Overview section.

Stage 0 (Carcinoma in Situ)

Treatment of stage 0 is usually local resection.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Stage I Anal Cancer

Treatment of stage I anal cancer may include the following:

  • Local resection.
  • External-beam radiation therapy with or without chemotherapy. If cancer remains after treatment, more chemotherapy and radiation therapy may be given to avoid the need for a permanent colostomy.
  • Internal radiation therapy.
  • Abdominoperineal resection, if cancer remains or comes back after treatment with radiation therapy and chemotherapy.
  • Internal radiation therapy for cancer that remains after treatment with external-beam radiation therapy.

Patients who have had treatment that saves the sphincter muscles may receive follow-up exams every 3 months for the first 2 years, including rectal exams with endoscopy and biopsy, as needed.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Stage II Anal Cancer

Treatment of stage II anal cancer may include the following:

  • Local resection.
  • External-beam radiation therapy with chemotherapy. If cancer remains after treatment, more chemotherapy and radiation therapy may be given to avoid the need for a permanent colostomy.
  • Internal radiation therapy.
  • Abdominoperineal resection, if cancer remains or comes back after treatment with radiation therapy and chemotherapy.
  • A clinical trial of new treatment options.

Patients who have had treatment that saves the sphincter muscles may receive follow-up exams every 3 months for the first 2 years, including rectal exams with endoscopy and biopsy, as needed.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Stage IIIA Anal Cancer

Treatment of stage IIIA anal cancer may include the following:

  • External-beam radiation therapy with chemotherapy. If cancer remains after treatment, more chemotherapy and radiation therapy may be given to avoid the need for a permanent colostomy.
  • Internal radiation therapy.
  • Abdominoperineal resection, if cancer remains or comes back after treatment with chemotherapy and radiation therapy.
  • A clinical trial of new treatment options.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Stage IIIB Anal Cancer

Treatment of stage IIIB anal cancer may include the following:

  • External-beam radiation therapy with chemotherapy.
  • Local resection or abdominoperineal resection, if cancer remains or comes back after treatment with chemotherapy and radiation therapy. Lymph nodes may also be removed.
  • A clinical trial of new treatment options.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Stage IV Anal Cancer

Treatment of stage IV anal cancer may include the following:

  • Surgery as palliative therapy to relieve symptoms and improve the quality of life.
  • Radiation therapy as palliative therapy.
  • Chemotherapy with radiation therapy as palliative therapy.
  • A clinical trial of new treatment options.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Disclaimer The content used in the pages is sourced from the National Cancer Institute Website ( www.cancer.gov )
Content Details Source URL : https://www.cancer.gov/types